5 Best Clinics in Downtown, Jackson MS
Updated 11 October 2026 · 17 clinics in Downtown, Jackson MS considered · Ranked from Google ratings
This list brings together five clinics and hospitals serving Downtown Jackson, Mississippi, for residents and visitors who need care nearby. Businesses are ranked by Google rating, weighted by the number of reviews each one has. Seventeen qualifying businesses were considered before the top five were selected. Hours, addresses and accessibility details are taken from each Google listing. The review notes summarize what reviewers mention, and they do not represent our own visits.
#1
Mississippi Sports Medicine & Orthopaedic Center
★ 4.7 (2,815 Google reviews)Orthopedic surgeon
Representative photo, not of this business.
An orthopedic practice at 1325 E Fortification St in Jackson, rated 4.7 from 2,815 reviews. It is open weekdays from 7:30 am to 5 pm and closed on weekends, and Google lists appointments as recommended. Reviewers mention a nurse practitioner who explained a procedure in easy terms, and surgeons they credit for helping them walk and travel without pain. The listing notes on-site parking, card and mobile payments, and wheelchair-accessible entrances and restrooms.
Best for: Joint and sports injury visits
- Address
- 1325 E Fortification St, Jackson, MS 39202, United States
- Hours
- Fri 7:30 am–5 pm; Mon 7:30 am–5 pm; Sat Closed; Sun Closed; Thu 7:30 am–5 pm; Tue 7:30 am–5 pm; Wed 7:30 am–5 pm
#2
TrustCare
★ 4.7 (718 Google reviews)Urgent care center
Representative photo, not of this business.
An urgent care center at 601 US-80 in Clinton, close to Jackson, with a 4.7 rating from 718 reviews. It is open weekdays from 8 am to 8 pm, Saturday and Sunday from 8 am to 5 pm. Reviewers mention a patient nurse who made vaccinations painless, a physician described as careful and attentive, and staff who were quick and efficient. One reviewer felt a doctor seemed dismissive during their visit. Wheelchair-accessible parking, entrance and toilet are listed.
Best for: Same-week urgent care visits
- Address
- 601 US-80, Clinton, MS 39056, United States
- Hours
- Fri 8 am–8 pm; Mon 8 am–8 pm; Sat 8 am–5 pm; Sun 8 am–5 pm; Thu 8 am–8 pm; Tue 8 am–8 pm; Wed 8 am–8 pm
#3
St. Dominic Hospital
★ 4.6 (9,286 Google reviews)Hospital
Representative photo, not of this business.
A hospital at 969 Lakeland Dr in Jackson that is open 24 hours a day, with 9,286 reviews on Google and a 4.6 rating. Reviewers praise emergency department staff for keeping them informed, and a nuclear imaging team for being courteous. Some reviewers described long waits with no wheelchair offered while they were in pain. The listing shows a wheelchair-accessible car park and entrance.
Best for: Emergency and imaging services
- Address
- St Dominic Hospital, 969 Lakeland Dr, Jackson, MS 39216, United States
- Hours
- daily Open 24 hours
#4
Mississippi Baptist Medical Center
★ 4.6 (6,053 Google reviews)General hospital
Representative photo, not of this business.
A general hospital at 1225 N State St in Jackson, open around the clock, rated 4.6 from 6,053 reviews. Reviewers mention a welcoming and timely admission process, a care team that stayed with a new mother through a complicated delivery, and an emergency department experience that one reviewer, a nurse herself, found concerning. The listing shows accessible parking, entrance, seating and restroom.
Best for: Hospital care and childbirth
- Address
- 1225 N State St, Jackson, MS 39202, United States
- Hours
- daily Open 24 hours
#5
Baptist Premier
★ 4.7 (329 Google reviews)Medical clinic
Representative photo, not of this business.
A medical clinic at 1200 N State St Suite 500, rated 4.7 from 329 reviews. Hours run Monday through Thursday from 8 am to 4:30 pm and Friday from 8 am to noon, with weekends closed. Reviewers mention a physician who is patient and gentle and always makes time for questions, reminder calls and check-out staff who are kind, and lab results that came back the same day. The listing shows accessible parking, entrance and toilet.
Best for: Routine checkups and same-day labs
- Address
- 1200 N State St Ste 500, Jackson, MS 39202, United States
- Hours
- Fri 8 am–12 pm; Mon 8 am–4:30 pm; Sat Closed; Sun Closed; Thu 8 am–4:30 pm; Tue 8 am–4:30 pm; Wed 8 am–4:30 pm
How we made this list
We looked at 17 clinics in Downtown, Jackson MS with a Google rating of 4.0 or higher and at least 20 reviews, then ranked by Google rating, weighted by how many people left one. A rating from thousands of reviews counts for more than the same rating from a handful, so a new place with a few perfect scores does not jump the queue. Ratings and hours are from public Google listings on 11 October 2026 and can change. Nobody paid to be on this list.
Tips before you go
- St. Dominic Hospital is listed as open 24 hours, so it works for a very early or very late visit.
- Hours and prices come from Google listings and change, so check the listing before a long trip.
Frequently asked questions
Which is the highest-rated clinic on this list?
Mississippi Sports Medicine & Orthopaedic Center ranks first, with a Google rating of 4.7 from 2,815 reviews. TrustCare is second at 4.7 from 718 reviews.
Which clinics in Downtown, Jackson MS are open late?
St. Dominic Hospital and Mississippi Baptist Medical Center are listed as open 24 hours.
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